We provide customizable in vivo cancer models and support services to help clients and researchers to evaluate novel anti-cancer therapies.

Specialty oncology models:

  • Xenografts - broad range of tumor lines or different origin
  • Breast, prostate, pancreatic, colon, ovarian, gastric, lung carcinoma, glioma, melanoma
  • Patient-Derived Xenografts (PDX) as explants established as models at low passage numbers
  • Gastric and ovarian carcinoma, glioma
  • Syngenetic models suitable for the evaluation of immunobiological-based therapies
  • Bl16F10 melanoma, 4T1 breast cancer, CT26 colon carcinoma
  • Subcutaneous  and orthotopic models
  • Various reporter constructs (luciferase, GFP and its derivatives)

 

Services

  • Tissue processing for histology
  • Construction of tissue arrays
  • Immunostaining, microscopy and interpretation
  • Efficacy and PK/PD analyses

 

Additional information www.cancerbiology.ee